Inflammatory bone loss: pathogenesis and therapeutic intervention

By K. Redlich, J. Smolen. Nature reviews. Drug discovery, 2012

790 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/e6ea56b2adc7df80f62aea7c6e019c7391cad18c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Daniel Aletaha
2. J. Smolen

In Oncology

1. Daniel Aletaha
2. J. Smolen

In Rheumatology

1. Daniel Aletaha
2. Martina Anzaghe
3. J. Smolen
4. Yen-Ju Lin
5. S. Schülke

Citations in the corpus

• Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis (2020, background): “In addition, RANK-L produced by cytokine-activated fibroblasts in combination with TNF-α and IL-6 from activated immune cells induces the differentiation of macrophages and preosteoclasts into osteoclasts that are specialized in the degradation of bone material [1,7,99].”
• Diagnosis and Management of Rheumatoid Arthritis: A Review (2018, positive): “Stimulation by RANKL, TNF, and IL-6 generates osteoclasts within the synovial membrane and promotes bony damage.(7) These molecular and cellular events result in the clinical disease expression.”