From bench to bedside

By L. Trümper. Medizinische Klinik, 2005

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Macrophages in immunoregulation and therapeutics (2023, background): “High mobility group box 1 (HMGB1), heat shock proteins (HSPs), and ATP are examples of DAMPs that are released when cells die in tumors.(283,284) Anti-tumor immunity may be boosted, for instance, when dendritic cells and macrophages are activated due to this stimulation.”
Spinal cord injury: molecular mechanisms and therapeutic interventions (2023, background): “As a sodium channel blocker, Riluzole blocks the sodium channels and prevents the excessive influx of sodium ions, reduces the intracellular sodium concentration and influx of calcium ions which cause the development of intracellular acidosis and cytotoxic edema.(338) In animal studies, riluzole pro”