Immunogenic cell death and DAMPs in cancer therapy

By D. Krysko, Abhishek D Garg, A. Kaczmarek, O. Krysko, P. Agostinis, Peter Vandenabeele. Nature Reviews. Cancer, 2012

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Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases (2017, neutral): “HMGB1 also stimulates production of pro-inflammatory cytokines, such as CXCL8 from neutrophils and macrophages and thus, accelerates ICD [343].”
Consensus guidelines for the detection of immunogenic cell death (2014, background): “, it can involve a genetically encoded molecular machinery;(4,5,21) (3) similar to their necrotic counterparts, apoptotic cells can sometimes be detected by the immune system and elicit an adaptive immune response specific for dead cell-associated antigens.(6,7,22,23) Thus, although apoptosis as a p”
The role of oxidative stress during inflammatory processes (2013, background): “…al., 2005), stroke (Schulze et al., 2013), circulatory shock and trauma (Andersson and Tracey, 2011), diabetes (Nogueira-Machado et al., 2011), cancer (Krysko et al., 2012), and arthritis (Harris et al., 2012), and it also acts as a key pro-inflammatory cytokine involved in the pathogenesis of…”