How does proteinuria cause progressive renal damage?

By M. Abbate, C. Zoja, Giuseppe Remuzzi. Journal of the American Society of Nephrology, 2006

793 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Oxidant Mechanisms in Renal Injury and Disease (2016, positive): “Itwasdem-onstratedthatCOX-2canenhanceproductionofROSand subsequentlyenhanceapoptosisinculturedmesangialand proximal tubular cells (PTCs).”
Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy (2011, background): “Extensive analyses of the mechanisms by which proteinuria causes renal injury have been published elsewher”