Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management.

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Review of Long-Wavelength Optical and NIR Imaging Materials: Contrast Agents, Fluorophores and Multifunctional Nano Carriers (2012, background): “Therefore, nanoparticles with dye localized in a hydrophobic core have several advantages: (1) the possibility of increased brightness due to the core volume increasing linearly with mass, (2) a large variety of dyes that cannot be made in hydrophilic form, or which are brighter in hydrophobic form,”