The connectome

By Olaf Sporns. 2020

The connectome refers to a comprehensive network map of the connectivity of the nervous system. Such network maps are composed of sets of neural elements, which may correspond to individual neurons or brain areas, and their interconnections, which may correspond to synaptic links or inter-areal pathways. Connectome maps, at a given level of scale, provide a complete and systematic account of brain connectivity that portrays a complete set of anatomical or physiological relationships. This chapter provides an overview of the origins and definitions of the concept and its application to structural and functional brain connectivity, brief surveys of the major findings on the topology of the human connectome and how its connectivity structure shapes dynamic brain activity, and a selection of current themes in the study of individual differences in development and clinical populations.

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1. Liyuan Wang
2. Jianjian Zhao
3. Qian Li
4. Xuchen Zhang
5. Yi Zhong
6. Bohan Zhao
7. Wantong Hu
8. Xingxing Zhang

Citations in the corpus

• Genetic dissection of mutual interference between two consecutive learning tasks in Drosophila (2022, background): “In Drosophila, sensory information from different modalities can be transmitted to the MB, the key site of associative learning, and converges to a small set of output neurons (MBONs) to guide different behaviors (Li et al., 2020; Modi, Shuai, & Turner, 2020).”
• Questions and controversies in the study of time-varying functional connectivity in resting fMRI (2020, unknown): “Regional and global release of these molecules can lead to drastic changes in the dynamics of neural circuits (Bargmann, 2012; Bargmann & Marder, 2013), and growing evidence suggests that neuro-modulatory systems play a key role in triggering and sculpting the reconfiguration of functional brain…”