Regional, directional, and age-dependent properties of the brain undergoing large deformation.

By M. Prange, S. Margulies. Journal of Biomechanical Engineering, 2002

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The biophysics of neuronal growth (2010, background): “than the immature [216, 225]; however, contradictory data show that with increasing age nervous tissue becomes stiffer”
Fifty Shades of Brain: A Review on the Mechanical Testing and Modeling of Brain Tissue (2019, background): “sies regarding previous results in the literature, where some suggested that brain tissue was isotropic [22,120, 137,91,22], but others showed that there were significant directional trends [134,165,85,53,52], we combined biomechanical testing of the same specimen in three orthogonal loading directi”
Mechanical properties of gray and white matter brain tissue by indentation (2015, background): “While some authors suggest that a two-term model provides a sufficiently accurate fit (Gefen and Margulies, 2004; Prange and Margulies, 2002), others prefer a three-term model, either plain (Elkin and Morrison, 2013; Tamura et al., 2007), or in combination with the cerebrospinal fluid in a…”