RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.

By F. Oswald, M. Winkler, Ying Cao, K. Astrahantseff, S. Bourteele, W. Knöchel, T. Borggrefe. 2005

104 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Raphael Kopan
2. F. Oswald
3. M. Ilagan
4. Patrick Rodriguez
5. T. Borggrefe
6. B. D. Giaimo
7. Z. Antonello
8. Laura Mira

Citations in the corpus

• A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes (2016, background): “Of note, this C-terminal KMT2D fragment (4588–5588) interacts as strongly as the previously described SHARPinteractor CtIP (19) (Figure 1D).”
• The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism (2009, background): “In the mammalian nucleus, although the CSL protein RBPjκ can form complexes with many ubiquitous corepressor proteins, such as CIR, FLH1C/KyoT2, and NCoR/SMRT (reviewed in Bray, 2006), it is SHARP/MINT/SPEN that has emerged as the critical repressor of Notch target genes in vivo (Oswald et al., 2005”