Integrated biomarker response: A useful tool for ecological risk assessment

By B. Beliaeff, T. Burgeot. Environmental Toxicology and Chemistry, 2002

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Chlorophyll a fluorescence induction: Can just a one-second measurement be used to quantify abiotic stress responses? (2018, methodology): “Instead, the PSi was calculated using a general algorithm called Integrated Biomarker Response (IBR) (Beliaeff and Burgeot 2002; for details, see the Appendix) which has previously been used in ecological studies of environmental stress (see e.g., Broeg and Lehtonen 2006, Ferreira et al. 2015a,b). D”
Combined toxicological effects of pesticides: A fish multi-biomarker approach (2014, positive): “Some authors suggest that the selection f an appropriate battery of biomarkers can avoid false-negative esponses obtained with a single biomarker (Beliaeff and Burgeot, 002; Linde-Arias et al., 2008). The main goal of the present work as to evaluate the toxicological effects of a combination of pest”
A novel “Integrated Biomarker Response” calculation based on reference deviation concept (2013, positive): “In a next step, the general mean (μ) and standard deviation (s) of Yi were computed as previously described by Beliaeff and Burgeot (2002), and Yi is standardized.”