Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilisation of the biofilm structure.

By Søren Molin, T. Tolker-Nielsen. Current Opinion in Biotechnology, 2003

706 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e3a0055fcc09c3ad812ffc6974c46426e528cc0b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

In Molecular Biology

Citations in the corpus

Biofilms: Microbial Cities of Scientific Significance (2014, background): “Studies have also confirmed the importance of conjugative and non conjugative plasmid in promoting biofilm formation due to the presence of factors favoring biofilm development [66-68].”
Antibiotic resistance of bacterial biofilms. (2010, background): “antibiotic resistance have actually been found in CF patients (33) (34).”
Microbiological corrosion: mechanism, control and impact—a review (2017, positive): “Lateral gene transfer is greatly facilitated in biofilms and leads to a more stable biofilm structure [37].”
Studying plasmid horizontal transfer in situ: a critical review (2005, background): “They provide a stable physical environment for cell–cell contact and extracellular DNA itself can contribute to the maintenance of biofilm structure (for review see Ref”
Enhanced Biofilm Formation and Increased Resistance to Antimicrobial Agents and Bacterial Invasion Are Caused by Synergistic Interactions in Multispecies Biofilms (2006, background): “Also, biofilms offer enhanced opportunities for interactions such as horizontal gene transfer and cometabolism (24, 34, 51).”
Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials. (2012, background): “In bacterial biofilms, the close proximity of microbial cells and a rich presence of eDNA constitute ideal conditions for the exchange of genetic material [87].”
Biofilm formation and the food industry, a focus on the bacterial outer surface (2010, background): “Vice versa, the high density of bacterial populations in biofilms can stimulate conjugation and plasmid dispersal (Hausner and Wuertz 1999; Molin and Tolker-Nielsen 2003) and can therefore contribute to the spread of resistance genes, which are often also carried on the plasmid (Bower and Daeschel 1”
Microbial Surface Colonization and Biofilm Development in Marine Environments (2015, background): “Surface colonization may be particularly important for the expression and secretion of biopolymer-targeted extracellular enzymes and for the transition of microbial cells to the competent state, in which the uptake and incorporation of extracellular DNA (eDNA) are effective (31, 50, 51).”
Extracellular DNA in soil and sediment: fate and ecological relevance (2009, background): “Molin and Tolker-Nielsen (2003) suggested that probably, bacteria did not develop competence in young biofilms because there was no accumulation to a sufficient high concentration of the competence-stimulating signal molecules.”
Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance (2020, background): “In addition, other factors involved in HGT would be the biomass surface, as it has been shown that high surface/volume ratios (in well-structured biofilms) increase the efficiency of plasmid transfer [183,184].”
Transparent exopolymer particles: Potential agents for organic fouling and biofilm formation in desalination and water treatment plants (2009, background): “It is important to note that the involvement of TEP in the early stages of biofilm formation does not exclude, but rather supplements, other known mechanisms of biofilm development that undoubtedly occur, such as attachment of individual bacterial cells, EPS proliferation, quorum sensing [41], gene ”