The transcriptional regulatory network in the drought response and its crosstalk in abiotic stress responses including drought, cold, and heat

By K. Nakashima, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki. Frontiers in Plant Science, 2014

811 citations recorded by the source corpus.

Drought negatively impacts plant growth and the productivity of crops around the world. Understanding the molecular mechanisms in the drought response is important for improvement of drought tolerance using molecular techniques. In plants, abscisic acid (ABA) is accumulated under osmotic stress conditions caused by drought, and has a key role in stress responses and tolerance. Comprehensive molecular analyses have shown that ABA regulates the expression of many genes under osmotic stress conditions, and the ABA-responsive element (ABRE) is the major cis-element for ABA-responsive gene expression. Transcription factors (TFs) are master regulators of gene expression. ABRE-binding protein and ABRE-binding factor TFs control gene expression in an ABA-dependent manner. SNF1-related protein kinases 2, group A 2C-type protein phosphatases, and ABA receptors were shown to control the ABA signaling pathway. ABA-independent signaling pathways such as dehydration-responsive element-binding protein TFs and NAC TFs are also involved in stress responses including drought, heat, and cold. Recent studies have suggested that there are interactions between the major ABA signaling pathway and other signaling factors in stress responses. The important roles of these TFs in crosstalk among abiotic stress responses will be discussed. Control of ABA or stress signaling factor expression can improve tolerance to environmental stresses. Recent studies using crops have shown that stress-specific overexpression of TFs improves drought tolerance and grain yield compared with controls in the field.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/e395ad41426b2a26942cf7221a2d171a048d00f7

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In Plant Science

1. S. Singla-Pareek
2. Z. Dar
3. Balwant Singh
4. R. Joshi
5. M. Seleiman
6. A. Bohra
7. A. Lone
8. A. Pareek

Citations in the corpus

• Abscisic Acid and Abiotic Stress Tolerance in Crop Plants (2016, background): “The major cis-regulatory element associated with expression of ABA-responsive-genes is the ABA-response element (ABRE: PyACGTGG/TC), which may require an ABREcoupling element (CE) for full function (Hobo et al., 1999; Zhang et al., 2005; Nakashima et al., 2014).”
• The Role of Stress-Responsive Transcription Factors in Modulating Abiotic Stress Tolerance in Plants (2020, background): “The activated ABFs directly bind to the ABA-responsive element (ABRE), a major cis-element in ABA-responsive genes [31], and activate the transcription of other stress-responsive transcription factors, such as NACs and AP2/ERFs, which are also responsible for the expression of stress-responsive gene”
• Drought Stress Impacts on Plants and Different Approaches to Alleviate Its Adverse Effects (2021, background): “The molecular level of stress-tolerant genes is in cross talk quantitative loci traits showing their interaction and cloning of the genes that are related to stress [118].”
• Transcription Factors and Plants Response to Drought Stress: Current Understanding and Future Directions (2016, positive): “Thus, precise manipulation of SNAC s with suitable promoter offers a promising way to substantially alter drought stress response in plants (Mei and Lizhong, 2011; Bang et al., 2013; Rusconi et al., 2013; Nakashima et al., 2014b).”
• Molecular responses to drought stress in plants (2017, neutral): “…factors), functional proteins that protect the cellular membranes, and other proteins such as late embryogenesis abundant proteins, antioxidants, osmotin, proteins associated with the uptake and transport of water and ions such as aquaporins, and sugar transporters (Nakashima et al. 2014).”