A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK

By J. Enserink, A. Christensen, J. Rooij, M. Triest, F. Schwede, H. Genieser, S. Døskeland, J. Blank, J. Bos. Nature Cell Biology, 2002

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Novel targets for Huntington’s disease in an mTOR-independent autophagy pathway (2008, background): “Virgin female flies of the genotype y w; gmr-httNterm(1-171)Q120 (gmrQ120)(22) were allowed to mate with male flies from an isogenised w(1118) stock(23) in food vials for 48 h.”
Transposition Driven Genomic Heterogeneity in the Drosophila Brain: A Dissertation (2012, neutral): “45 Figure III-1: Mechanisms of neuronal diversity .................................................... 63 Figure AI-1: Testing olfactory memory in flies ..................................................... 82 Figure AI-2: Learning and memory deffects in EpacS flies .................................”
PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. (2005, background): “O-Me-cAMP fully activates cAMP-GEFI/Epac1 (156).”
GEFs and GAPs: critical elements in the control of small G proteins. (2007, background): “A selective agonist of Epac, 8-pCPT-2′OMe-cAMP, has been developed (Enserink et al., 2002) that counteracts a decrease in endothelial permeability caused by leakage-inducing agents such as thrombin and VEGF.”