The Consensus Coding Sequences of Human Breast and Colorectal Cancers

By T. Sjöblom, Siân Jones, L. Wood, D. W. Parsons, Jimmy Lin, T. Barber, D. Mandelker, R. Leary, Janine Ptak, Natalie Silliman and 19 more. Science, 2006

2,786 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/e2c9e82731305bb7da1e74f023e10c18ad3744bd

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Citations in the corpus

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction (2009, neutral): “Large-scale sequencing of multiple cancers has so far failed to identify new, high-frequency mutation targets in addition to those previously identified (Cancer Genome Atlas Research Network, 2008; Ding et al., 2008; Jones et al., 2008; Parsons et al., 2008; Sjoblom et al., 2006; Wood et al., 2007).”
Next-generation DNA sequencing (2008, background): “…an example of the advantages of the new platforms, consider that large-scale resequencing studies for identifying germline variation or somatic mutations have relied on Sanger-based resequencing approaches, that in turn are reliant on one-at-a-time PCR amplification of each targeted region 31,32 .”
Outcome of a Workshop on Applications of Protein Models in Biomedical Research (2009, background): “Many more data of this type are expected shortly (Di Bernardo et al., 2008; Sjoblom et al., 2006; Stacey et al., 2008).”
Comparative lesion sequencing provides insights into tumor evolution (2008, methodology): “DNA samples from tumor samples or their derived xenografts or cell lines were obtained and purified by using slight modifications of those described (13).”
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzymatic activity that converts α-ketoglutarate to 2-hydroxyglutarate (2010, background): “Mutations have also been reported in cancers of the colon and prostate (Kang et al., 2009; Sjoblom et al., 2006).”
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients (2008, background): “Notwithstanding this close relationship, cancer genome sequencing experiments have uncovered a multiplicity of mutated gene products that derive from defects in tumor cell DNA repair mechanisms (30, 31).”
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers (2011, background): “A common approach to identifying drivers is to study large collections of cancer samples, on the notion that regions containing driver events should be altered at higher frequencies than regions containing only passengers [4,6,7,9-14].”