Single-cell dynamics of genome-nuclear lamina interactions.

By Jop Kind, Ludo Pagie, H. Ortabozkoyun, S. Boyle, Sandra S. de Vries, H. Janssen, Mario Amendola, L. Nolen, Wendy A. Bickmore, B. van Steensel. Cell, 2013

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Topologically-associating domains are stable units of replication-timing regulation (2014, positive): “Although 30% of TTRs did not overlap with a computationally called LAD, these TTRs still associated with the nuclear lamina to some degree (EDF2f) and may interact preferentially with other repressive sub-nuclear compartments 19–21 .”