Mild to Moderate Muscular Symptoms with High-Dosage Statin Therapy in Hyperlipidemic Patients —The PRIMO Study
By E. Bruckert, G. Hayem, S. Dejager, C. Yau, B. Bégaud. Cardiovascular Drugs and Therapy, 2005
1,235 citations recorded by the source corpus.
Subfields: Emergency Medicine, Physiology, Surgery
View Paper: https://www.semanticscholar.org/paper/e1dcecc1219e840aaa46cd293956dd4acbad964d
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In Emergency Medicine
In Physiology
In Surgery
- I. Graham
- Marja-Riitta Taskinen
- J. Armitage
- George Davey Smith
- R. Collins
- M. Law
- Alberico L. Catapano
- P. Ridker
Citations in the corpus
- 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk. (2019, background): “Patients taking statin therapy frequently report muscle symptoms [so-called ‘statin-associated muscle symptoms’ (SAMS)], and in nonrandomized, observational studies, statins are associated with muscular pain and tenderness (myalgia) without CK elevation or major functional loss, with the reported fr”
- 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. (2016, background): “On the other hand, the reported frequency varies between 10 and 15% in observational studies.(215,216)”
- CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM--2016 EXECUTIVE SUMMARY. (2016, background): “Furthermore, statin intolerance (usually muscle-related adverse effects) can limit the use of intensive statin therapy in some patients (189).”
- Interpretation of the evidence for the efficacy and safety of statin therapy. (2016, background): “The Prédiction du Risque Musculaire en Observationnel (PRIMO) survey tried to overcome this limitation by systematically seeking information about the muscle symptoms that were reported.(244) Among 7924 hyperlipidaemic patients receiving high-dose statin therapy, 10.”
- Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management (2015, neutral): “The symptoms appear to be more frequent in physically active individuals.(11) Statin-associated muscle symptoms often appear more promptly when patients are re-exposed to the same statin.”