The sphingolipid salvage pathway in ceramide metabolism and signaling.

By K. Kitatani, J. Idkowiak-Baldys, Yusuf A. Hannun. Cellular Signalling, 2008

626 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/e1cc49bfeb0bdfcb058a5fbee0cbf7a6b2a89e7a

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In Molecular Biology

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Citations in the corpus

• The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction. (2012, neutral): “For example, in some cell types, the majority of nascent glycosphingolipids are synthesized from endolysosome-derived sphingoid bases derived from ceramide catabolism (Tettamanti, 2004; Kitatani et al., 2008).”
• Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium (2008, background): “When NPC1 protein is inactivated, sphingosine rapidly accumulates in the lysosome, and there is reduced efflux of sphingosine from the lysosome, which is a key step in the salvage pathway of GSL biosynthesis and S1P generatio”