Surface Hydration: Principles and Applications Toward Low-fouling/nonfouling Biomaterials

By Shenfu Chen, Lingyan Li, Chao Zhao, Jie Zheng. 2010

1,516 citations recorded by the source corpus.

Surface resistance to nonspecific protein adsorption, cell/bacterial adhesion, and biofilm formation is critical for the development and performance of biomedical and analytical devices. Significant needs and efforts have been made in the development of biocompatible and bioactive materials for antifouling surfaces, but much of the work retains an empirical flavor due to the complexity of experiments and the lack of robust theoretical models. In this review, two major classes of nonfouling materials (i.e. hydrophilic and zwitterionic materials) and associated basic nonfouling mechanisms and practical examples are discussed. Highly hydrated chemical groups with optimized physical properties of the surface, along with appropriate surface coating methods, are the keys to developing effective and stable nonfouling materials for long-term biomedical applications. The zwitterionic polymers are promising nonfouling biomaterials due to the simplicity of synthesis, ease of applicability, abundance of raw materials, and availability of functional groups.

Subfields: Biomedical Engineering, Ocean Engineering, Surfaces, Coatings and Films

View Paper: https://www.semanticscholar.org/paper/e1cc36a55824c3dc361e068bf0e1054d9a2e3ddd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. Yushan Yan
2. Dan Li
3. Huanting Wang
4. Enrico Drioli
5. Jun Yin
6. B. Deng
7. Seeram Ramakrishna
8. D. Mattia

In Surfaces, Coatings and Films

1. Jie Zheng
2. Enrico Drioli

Citations in the corpus

• Investigating the potential of membranes formed by the vapor induced phase separation process (2020, background): “worldwide have been developing filters able to maintain a high level of hydration at the interface between the membrane and the medium, an essential design criterion [256,258].”
• Recent advances in polymer and polymer composite membranes for reverse and forward osmosis processes (2016, background): “[135, 169-175] The zwitterionic carboxylated PEI-coated SWRO membrane presented lower contact angle to 32000 ppm of NaCl solution compared with that to DI water, suggesting higher affinity to NaCl solution and improved antifouling property in seawater condition.”