The Halogen Bond

By G. Cavallo, P. Metrangolo, R. Milani, T. Pilati, Arri Priimagi, Giuseppe Resnati, Giancarlo Terraneo. Chemical Reviews, 2016

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The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.

Subfields: Biomaterials, Physical and Theoretical Chemistry, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/e19dc58a3c19884835d0e2c2badfe1ae0a4ec1bc