Dynamic organization of chromatin domains revealed by super-resolution live-cell imaging

By Maeshima Kazuhiro. 2017

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Organization of Chromatin by Intrinsic and Regulated Phase Separation (2019, result): “This idea is consistent with various models of liquid-like organization of the genome (Dubochet et al., 1986; Maeshima et al., 2016a; Mirny et al., 2019; Nozaki et al., 2017), and suggest that previous reports of in vitro chromatin aggregates (Maeshima et al.”
Xist nucleates local protein gradients to propagate silencing across the X chromosome (2021, background): “The confined motion of Xist foci is highly correlated with the motion of chromatin loci (Chen et al., 2013; Nozaki et al., 2017).”
Topological polymorphism of nucleosome fibers and folding of chromatin (2021, result): “It would be interesting to compare these results with the superresolution imaging data (11,13).”