Refined structure of alpha beta-tubulin at 3.5 A resolution.

By J. Löwe, Huilin Li, K. Downing, E. Nogales. Journal of Molecular Biology, 2001

973 citations recorded by the source corpus.

Subfields: Cell Biology, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/df311b85650665514ebfb117c050f2e33d834e7c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Gabriel Lander
2. Arpita Mitra
3. L. Sibley
4. N. Morrissette
5. P. Verdier-Pinard
6. S. Horwitz
7. G. Orr
8. H. McDaid

In Materials Chemistry

1. Elizabeth H. Kellogg
2. David Baker
3. Gabriel Lander
4. E. Nogales
5. Tanja Kortemme
6. Yang Zhang
7. Jeffrey J. Gray
8. Jens Meiler

In Molecular Biology

1. Elizabeth H. Kellogg
2. David Baker
3. Gabriel Lander
4. Arpita Mitra
5. L. Sibley
6. N. Morrissette
7. P. Verdier-Pinard
8. S. Horwitz

Citations in the corpus

• High resolution microtubule structures reveal the structural transitions in αβ–tubulin upon GTP hydrolysis (2014, methodology): “We infer that this structural transition is coupled to the movement we observe for the T7 loop and helix H8 of the adjacent a subunit, which contains the presumed catalytic residue Glu254 (Löwe et al., 2001), as this region translates nearly 2 Å in a direction that matches the motion of the a-tubu”
• Dinitroanilines Bind α-Tubulin to Disrupt Microtubules (2004, background): “Several of the resistance mutations are located in the M or N loops, regions of tubulin that mediate lateral adhesion of protofilaments (Downing and Nogales, 1998a; Nogales et al., 1998, 1999; Lowe et al., 2001).”
• Mechanisms of Taxol resistance related to microtubules (2003, background): “Recently, models with improved resolution have been published (Lowe et al., 2001; Meurer-Grob et al., 2001).”