Personalized vaccines for cancer immunotherapy

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Regulatory mechanisms of PD-1/PD-L1 in cancers (2024, background): “Compared to chemotherapy and radiotherapy, cancer vaccines usually have minimal side effects [447].”
mRNA-based therapeutics: powerful and versatile tools to combat diseases (2022, background): “Neoepitopes can bypass central tolerance with high immunogenicity because they are never present in normal tissues and generate the accumulation of gene mutations in cancer cells (including driver mutations and passenger mutations).(379) Therefore, neoepitopes were applied to overcome the central to”