Biology and therapeutic potential of interleukin-10

By M. Saraiva, P. Vieira, A. O’Garra. Journal of Experimental Medicine, 2019

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The authors review the molecular mechanisms regulating IL-10 production and response and describe classic and novel functions of IL-10 in immune and non-immune cells. They further discuss the therapeutic potential of IL-10 in different diseases and the outstanding questions underlying an effective application of IL-10 in clinical settings.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/de1c1f07eb6fabd94c685e6ebb1407e6f75355bc