What recent ribosome structures have revealed about the mechanism of translation

By T. Schmeing, V. Ramakrishnan. Nature, 2009

720 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation (2020, background): “Discussion Ribosomes contain multiple binding sites intended to accommodate substrates of different natures: tRNAs, mRNAs, or protein factors (7).”
Studies on the role of helix 69 of 23S rRNA in the factor-dependent stages of translation initiation, elongation, and termination (2011, background): “…rounds of elongation include aminoacyl-tRNA binding to the ribosomal A-site, peptide bond formation in the peptidyl transferase centre and translocation of the tRNA-mRNA complex by one codon at a time to make the next codon available to a new elongator tRNA (Schmeing and Ramakrishnan 2009).”
Integrative structure modeling with the Integrative Modeling Platform (2017, methodology): “24 The integrative structure determination procedure used here 18,25,26 is schematically shown in Figure 1.”
Rethinking amide bond synthesis (2011, neutral): “GLP-1 (22-36) Interleukin-8 (35-72) I n t e r l e u k i n 8 ( 1 3 3 )RNase A (11 –124) G L P 1 ( 2 2 3 6 ) I n t e r l e u k i n 8 ( 3 5 7 2 ) Interleukin-8 (1-33) RNase A (110–111)”