The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders.
By W. Miller, R. Auchus. Endocrine reviews, 2011
2,139 citations recorded by the source corpus.
Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/dd04ce44c29ee94d02eeab3acd9a2c5288bf6c3b
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In Endocrinology, Diabetes and Metabolism
In Molecular Biology
Citations in the corpus
- Leydig cells: formation, function, and regulation† (2018, background): “Four steroidogenic enzymes are involved in testosterone biosynthesis from cholesterol: Cytochrome P450 Family 11 Subfamily A1 (CYP11A1), 3β-hydroxysteroid dehydrogenase/ 5 → 4 isomerase (3β-HSD), CYP17A1, and 17β-HSD3 [50, 51].”
- Mechanistic Pathways of Sex Differences in Cardiovascular Disease. (2017, background): “Androgens are mainly produced in the Leydig cells of the testis but also to a lesser extent by the adrenal gland, in the adipose tissue and bone (34, 268).”
- The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. (2016, background): “do not do so because they do not express CYP17A1 (62).”
- Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline. (2016, background): “In newborns and children, mineralocorticoid sensitivity is lower, thereby usually requiring higher fludrocortisone doses compared to adults (106).”