Rational Design of Cancer Nanomedicine: Nanoproperty Integration and Synchronization

By Qihang Sun, Zhuxian Zhou, Nasha Qiu, Youqing Shen. Advances in Materials, 2017

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Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems (2018, background): “For instance, DaunoXome (a nanoliposomal anticancer formulation) consists of 50–80 nm diameter particles intended to reduce MPS uptake [43,44].”
Nanomedicine in cancer therapy (2023, background): “39,40 44 For example, relatively large sizes (50 – 200 nm), near-neutral charges, and shielded cell-/organelle-targeting ligands favor nanoparticle blood circulation and tumor accumulation, while smaller sizes ( 20 nm), positive charges, and re-exposed/activated targeting ligands are expected to…”