Recent advances of chitosan nanoparticles as drug carriers

By Jun Jie Wang, Zhaowu Zeng, Renzhong Xiao, Tian Xie, G. Zhou, Xiaori Zhan, Shu Wang. International Journal of Nanomedicine, 2011

657 citations recorded by the source corpus.

Chitosan nanoparticles are good drug carriers because of their good biocompatibility and biodegradability, and can be readily modified. As a new drug delivery system, they have attracted increasing attention for their wide applications in, for example, loading protein drugs, gene drugs, and anticancer chemical drugs, and via various routes of administration including oral, nasal, intravenous, and ocular. This paper reviews published research on chitosan nanoparticles, including its preparation methods, characteristics, modification, in vivo metabolic processes, and applications.

Subfields: Biomaterials, Pharmaceutical Science, Surfaces, Coatings and Films

View Paper: https://www.semanticscholar.org/paper/dc552adb68c25a111a5bd6d38169123615733303

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8. K. Wasan

Citations in the corpus

• An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery (2017, background): “However, the toxicity of chitosan increases by increasing charge density and degree of deacetylation [37].”
• Does the Use of Chitosan Contribute to Oxalate Kidney Stone Formation? (2014, background): “Most of the chitosan-based nanocomposites, when administered to animals or patients, release chitosan into the blood stream [9].”