Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4.
By F. Semeraro, C. Ammollo, J. Morrissey, G. Dale, P. Friese, N. Esmon, C. Esmon. Blood, 2011
851 citations recorded by the source corpus.
Subfields: Hematology, Immunology, Immunology and Allergy
View Paper: https://www.semanticscholar.org/paper/d91a16160727f11f182ce3df812d85b894530282
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In Immunology
Citations in the corpus
- Thrombosis: tangled up in NETs. (2014, background): “Also, histones increase thrombin generation(37) in a platelet-dependent manner.(38) Histones activate platelets,(31) and platelet activation, in turn, promotes coagulation.”