Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database.

By N. Mehta, R. Azfar, D. Shin, A. Neimann, Andrea B. Troxel, J. Gelfand. European Heart Journal, 2010

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Reactive Oxygen Species in Inflammation and Tissue Injury (2014, neutral): “There is an interesting correlation between Ang II-mediated activation of the immune system and hypertension (158, 450) with the increased risk of hypertension and cardiovascular mortality in psoriasis patients that is associated with elevated levels of Ang II (253, 285).”
Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease (2019, background): “Furthermore, psoriasis has even been characterized as an independent risk factor for cardiovascular disease [4] where patients presenting with psoriasis or associated inflammatory arthritis are recommended by the European League Against Rheumatism to undergo cardiovascular therapy [159].”
European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012) (2012, positive): “Patients in whom the psoriasis was classified as severe had a higher risk of myocardial infarction than patients with mild psoriasis, consistent with the hypothesis that greater immune activity in psoriasis is related to a higher risk of myocardial infarction and cardiovascular death.(185,186)”