Electrospun Scaffolds for Tissue Engineering of Vascular Grafts

By A. Hasan, A. Memić, N. Annabi, Monowar Hossain, A. Paul, Mehmet Remzi Dokmeci, Fariba Dehghani, Ali Khademhosseini. Acta Biomaterialia, 2013

671 citations recorded by the source corpus.

There is a growing demand for off-the-shelf tissue engineered vascular grafts (TEVGs) for replacement or bypass of damaged arteries in various cardiovascular diseases. Scaffolds from the decellularized tissue skeletons to biopolymers and biodegradable synthetic polymers have been used for fabricating TEVGs. However, several issues have not yet been resolved, which include the inability to mimic the mechanical properties of native tissues, and the ability for long term patency and growth required for in vivo function. Electrospinning is a popular technique for the production of scaffolds that has the potential to address these issues. However, its application to human TEVGs has not yet been achieved. This review provides an overview of tubular scaffolds that have been prepared by electrospinning with potential for TEVG applications.

Subfields: Biomaterials, Electronic, Optical and Magnetic Materials, Surgery

View Paper: https://www.semanticscholar.org/paper/d97d1ef83cca07bacebc210db5606f498191d0d4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Mahboob Morshed
2. A. Hasan
3. A. Memić
4. Shabir Hassan
5. Thomas J. Webster
6. Hany E. Marei

Citations in the corpus

• Nanoparticles in tissue engineering: applications, challenges and prospects (2018, background): “1,2 The scaffolds are used as three-dimensional (3D) structures in which cells grow, proliferate and differentiate into various cell types.”