Prevalence of chronic kidney disease in population-based studies: Systematic review

By Qiu-li Zhang, D. Rothenbacher. BMC Public Health, 2008

1,045 citations recorded by the source corpus.

BackgroundChronic kidney disease (CKD) is becoming a major public health problem worldwide. This article reviews the published evidence of prevalence of CKD in population-based study samples that used the standardized definition from the Kidney Disease Outcomes Quality Initiative of the National Kidney Foundation (K/DOQI) practice guideline, and particularly focus on performance of serum-creatinine based equations for GFR estimation. We provide a summary of available data about the burden of CKD in various populations.MethodsWe performed a systematic review of available published data in MEDLINE. A combination of various keywords relevant to CKD was used in this research. Related data of included studies were extracted in a systematic way.ResultsA total of 26 studies were included in this review. The studies were conducted in different populations, and the number of study participants ranged from 237 to 65181. The median prevalence of CKD was 7.2% in persons aged 30 years or older. In persons aged 64 years or older prevalence of CKD varied from 23.4% to 35.8%. Importantly, the prevalence of CKD strongly depended on which estimating equations were used. The Modification of Diet in Renal Disease Study (MDRD) equation was likely to be preferred in recent epidemiological studies compared to the adjusted Cockcroft-Gault (CG) equation.ConclusionWorldwide, CKD is becoming a common disease in the general population. Accurately detecting CKD in special groups remains inadequate, particularly among elderly persons, females or other ethnic groups such as Asians.

Subfields: Cardiology and Cardiovascular Medicine, Nephrology

View Paper: https://www.semanticscholar.org/paper/d8b3c44df765eb614227ee433b658dfcf9e7a9b5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. A. Levin
2. J. Griffith
3. D. Naimark
4. L. Stevens
5. A. Levey
6. H. Tighiouart
7. N. Tangri
8. O. Djurdjev

In Nephrology

1. A. Levey
2. L. Stevens
3. Marcello Tonelli
4. A. Levin
5. Giuseppe Remuzzi
6. Josef Coresh

Citations in the corpus

• Two Novel Equations to Estimate Kidney Function in Persons Aged 70 Years or Older (2012, background): “This is especially true for older adults, in whom prevalence rates vary in the literature between one third and nearly one half of the general population (4-9), impressive numbers that have raised controversy among experts about the clinical relevance of the CKD diagnosis in this age group.”
• A predictive model for progression of chronic kidney disease to kidney failure. (2011, background): “Similar estimates of burden of disease have been reported around the world.(6) Although there are proven therapies to improve outcomes in patients with progressive kidney disease, these therapies may also cause harm and add cost.”
• The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. (2011, background): “causes severe financial hardship for those who have access to it.(2) Another 112 countries, with a combined population”