Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
By J. McCubrey, Linda S. Steelman, Stephen L. Abrams, John T. Lee, F. Chang, F. E. Bertrand, P. Navolanic, D. Terrian, R. Franklin, A. D'Assoro and 4 more. Advances in Enzyme Regulation, 2006
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Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/d888403f3f7dc2581eba0ea93edb97ae8e2dbe0c
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In Molecular Biology
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- PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer (2023, background): “Moreover, AKT overactivation has been observed in several other types of cancers [77, 122, 123, 80, 78, 82, 75] (Fig.”