Microfluidic device for single-cell analysis.
By Aaron R. Wheeler, W. Throndset, R. Whelan, A. Leach, Richard N. Zare, Y. Liao, K. Farrell, I. Manger, A. Daridon. Analytical Chemistry, 2003
606 citations recorded by the source corpus.
Subfields: Bioengineering, Biomedical Engineering
View Paper: https://www.semanticscholar.org/paper/d80ff9de9c64ac1e968e791a9c3ca6a8238742eb
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In Biomedical Engineering
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Citations in the corpus
- Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells (2015, methodology): “Protocols have been developed to overcome these limitations by amplifying small quantities of mRNA 4,5 , which, in combination with microfluidics approaches for isolating individual cells 6,7 , have been used to analyze the co-expression of tens to hundreds of genes in single cells 8,9 .”
- Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans (2007, methodology): “In previous studies, microfluidic delivery systems have been used to trap and stimulate single cells and embryo”
- Direct, one-step molding of 3D-printed structures for convenient fabrication of truly 3D PDMS microfluidic chips (2015, methodology): “2006), single-cell analysis (Wheeler et al. 2003; Wu et al. 2004; Huang et al. 2007) and 3D chaotic advective mixer (Vijayendran et al.”
- The origins and the future of microfluidics (2006, background): “, examination and manipulation of samples consisting of a single cel”
- Microfluidics: Fluid physics at the nanoliter scale (2005, background): “32 Hansen et al., 2002 , and protein solubility chip Hansen et al., 2004 , flow injection devices Leach et al., 2003 , and cell analyzers and sorters Fu et al., 2002; Wheeler et al., 2003 .”
- Cells on chips (2006, background): “This makes it possible to monitor very fast cellular responses, such as calcium flux in ionomycin-stimulated Jurkat cell”