The Advancing of Zinc Oxide Nanoparticles for Biomedical Applications
By Jin-huan Jiang, Jiang Pi, Jiye Cai. Bioinorganic Chemistry and Applications, 2018
1,093 citations recorded by the source corpus.
Zinc oxide nanoparticles (ZnO NPs) are used in an increasing number of industrial products such as rubber, paint, coating, and cosmetics. In the past two decades, ZnO NPs have become one of the most popular metal oxide nanoparticles in biological applications due to their excellent biocompatibility, economic, and low toxicity. ZnO NPs have emerged a promising potential in biomedicine, especially in the fields of anticancer and antibacterial fields, which are involved with their potent ability to trigger excess reactive oxygen species (ROS) production, release zinc ions, and induce cell apoptosis. In addition, zinc is well known to keep the structural integrity of insulin. So, ZnO NPs also have been effectively developed for antidiabetic treatment. Moreover, ZnO NPs show excellent luminescent properties and have turned them into one of the main candidates for bioimaging. Here, we summarize the synthesis and recent advances of ZnO NPs in the biomedical fields, which will be helpful for facilitating their future research progress and focusing on biomedical fields.
Subfields: Biomaterials, Materials Chemistry, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/d801669f3f66652c86721c93edeb34538960b050
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Citations in the corpus
- Metal-Based Nanoparticles as Antimicrobial Agents: An Overview (2020, background): “Several studies demonstrated that ZnONPs cause genotoxic effects including DNA damage in neuronal and human epidermal cancer cells [156].”
- Zinc Oxide for Functional Textile Coatings: Recent Advances (2019, background): “Since these green routes are especially important for biomedical applications, the photocatalytic, antibacterial, antifungal, drug delivery, anticancer, antidiabetic, anti-inflammatory as well as bioimaging activities of ZnO NPs were taken into consideration [32,33].”
- Synthesis and applications of ZnO nanostructures (ZONSs): a review (2021, background): “ZONSs against a number of Gram-positive and Gramnegative pathogens.([90]) The main factor for excellent”