Spatial proteomics: a powerful discovery tool for cell biology

By E. Lundberg, Georg H. H. Borner. Nature reviews. Molecular cell biology, 2019

504 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/d791ecf4e4ada2ccadd113a1d2962976b12f400e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Fabian J Theis
2. Jonathan S. Weissman
3. C. Hetz
4. G. Hotamışlıgil

In Molecular Biology

1. Malte D. Luecken
2. Fabian J Theis
3. Luke Zappia
4. H. Schiller
5. Anna C. Schaar
6. F. Drost
7. Christopher Lance
8. Anastasia Litinetskaya

In Spectroscopy

1. Marco Y. Hein
2. Andreas-David Brunner

Citations in the corpus

• Methods and applications for single-cell and spatial multi-omics (2023, background): “Principles of spatial mono-omics methods for spatial multi-omics developments Methods for spatial mono-omics have progressed tremendously in the last decade with excellent reviews existing for spatial transcriptomics 165,171–173 , (epi)genomics 166,174 , proteomics 86,167 and metabolomics 168,175 .”
• Empowering Biomedical Discovery with AI Agents (2024, unknown): “…omics, super-resolution microscopy, and gene editing have generated datasets on normal and perturbed cells, covering areas such as multi-omics [98– 100], cell viability [101], morphology [102], cryo-electron microscopy and tomography [103, 104], and multiplexed spatial proteomics [105, 106].”
• OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization (2022, background): “Therefore, several approachesneed tobe combined for its elucidation (5).”
• Best practices for single-cell analysis across modalities (2023, background): “Tangram 224 , GridNet 230 and eggplant 231 generate common coordinate frameworks across samples to mitigate this issue 232 .”
• An introduction to spatial transcriptomics for biomedical research (2022, background): “Nevertheless, some approaches have been devised, with broad approaches such as mass spectrometry analysis of fractionated organelles to identify enriched proteins, affinity-purification mass spectrometry to identify interactions by profiling proteins bound to their partners, and imaging-based proteo”