Effect of Allium sativum on the immunity and survival of Labeo rohita infected with Aeromonas hydrophila

By S. Sahu, B. Das, B. K. Mishra, J. Pradhan, N. Sarangi. 2007

301 citations recorded by the source corpus.

Summary The aim of this study was to evaluate dietary dosages of garlic on the immune response and disease resistance against infections due to the opportunistic pathogen Aeromonas hydrophila in Labeo rohita fingerlings. Garlic, Allium sativum, was incorporated into the diets (0%, 0.1%, 0.5% and 1.0%) of rohu, L. rohita fingerlings (10 ± 2 g). Every 20 days, different biochemical (serum total protein, albumin, globulin, albumin : globulin ratio, blood glucose), haematological (WBC, RBC and haemoglobin content) and immunological (superoxide anion production, lysozyme activity and serum bactericidal activity) parameters were evaluated. Superoxide anion production, lysozyme, serum bactericidal, serum protein and albumin were enhanced in garlic treated groups compared with the control group. After 60 days, fish were challenged with A. hydrophila and mortality (%) was recorded up to day 10 post-challenge. Survival decreased in control group (57%) up to day 10 after infection. However, this was increased in the garlic treatment group, i.e. 85% survivability in the 1 g garlic kg−1 (B group) and 5 g garlic kg−1 (C group), and 71% survivability in the 10 g garlic kg−1 (D group), respectively. These results indicate that Allium sativum stimulates the immunity and makes L. rohita more resistant to infection by A. hydrophila.

Subfields: Immunology, Pharmacology, Plant Science

View Paper: https://www.semanticscholar.org/paper/d6c883a584093e7435ec10ae262388b0852da93c

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In Immunology

In Plant Science

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Citations in the corpus

Dietary supplementation of garlic (Allium sativum) to prevent monogenean infection in aquaculture (2013, background): “…the teleost immune system by conferring direct antimicrobial activity to serum, increasing the number of leucocytes and by increasing phagocytic, lysozyme, and anti-protease activities (Aly and Mohamed, 2010; Nya and Austin, 2009; Nya et al., 2010; Sahu et al., 2007; Talpur and Ikhwanuddin, 2012).”
Boosting Immune Function and Disease Bio-Control Through Environment-Friendly and Sustainable Approaches in Finfish Aquaculture: Herbal Therapy Scenarios (2020, methodology): “Garlic (Allium sativum): In a 60-days feeding trial, Sahu et al. (2007) evaluated the anticipated disease protection properties of different levels (1, 5, and 10 g kg 1) of dietary garlic (Allium sativum) in rohu fingerlings (10 ± 2 g).”