Good and poor adherence: optimal cut-point for adherence measures using administrative claims data

By S. Karve, M. Cleves, M. Helm, T. Hudson, D. West, B. Martin. Current Medical Research and Opinion, 2009

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The effectiveness of interventions using electronic reminders to improve adherence to chronic medication: a systematic review of the literature (2012, background): “In adherence research, a patient is often classified as adherent when an adherence rate of over 80% is reached.(59) This cut-off point indicates the minimum level of adherence needed for therapeutic effect.”
Early discontinuation and non-adherence to adjuvant hormonal therapy are associated with increased mortality in women with breast cancer (2010, background): “, the medication possession ratio (MPR), was greater than or equal to 80%, a definition commonly used in the adherence literature [22, 23].”