Extension of the frontiers of surgical indications in the treatment of liver metastases from colorectal cancer: long-term results.

By M. Minagawa, M. Makuuchi, G. Torzilli, T. Takayama, S. Kawasaki, T. Kosuge, J. Yamamoto, H. Imamura. Annals of Surgery, 2000

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Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases (2005, background): “Recent improvement in whole-body and hepatic imaging has allowed for more accurate selection of patients with CRM. Preoperative imaging is now able to detect minimal burdens of metastatic disease that in the past would have been detected only after enlarging and thus would have been classified at a ”
Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy: A Model to Predict Long-term Survival (2004, background): “Since some years, this has been challenged by some groups, including ours.(1,3,10,11,29,37,38) However, extrahepatic tumor has been commonly reported as a factor of poor prognosis.”
Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. (2004, background): “Hepatic resection currently remains the treatment that offers the best chance of long-term survival to such patients [2, 3].”