Gene regulation by riboswitches

By Maumita Mandal, Ronald R. Breaker. Nature reviews. Molecular cell biology, 2004

881 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/d5af5172a2d7b53f9d54442487f5558c8286cacf

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In Molecular Biology

Citations in the corpus

A comprehensive comparison of comparative RNA structure prediction approaches (2004, background): “(2) There are 'ribo-switches', whereby two or more functional structures exist for a given sequence [55-57].”
Rfam: annotating non-coding RNAs in complete genomes (2004, background): “bacterial riboswitches bind a range of metabolites as reviewed previously (7,8), and the 50-UTR of the PrfA acts as a temperaturedependent switch (9)] to regulate message stability or translational efficiency.”
Regulatory RNAs in Bacteria (2009, background): “…the aptamer region, which binds the ligand, and the so-called expression platform, which regulates gene expression through alternative RNA structures that affect transcription or translation (reviewed in Mandal and Breaker, 2004; Montange and Batey, 2008; Nudler and Mironov, 2004) (Figure 1A).”
RNA thermometers are common in α- and γ-proteobacteria (2005, background): “However, since numerous RNA sensors have been established during evolution (Mandal and Breaker, 2004; Winkler, 2005), economic considerations might not always be of highest priority for survival in an ever-changing environment.”
3dRNA v2.0: An Updated Web Server for RNA 3D Structure Prediction (2019, background): “Noncoding RNAs can catalyze and regulate many biochemical reactions in organisms [1].”
Aptamers come of age – at last (2006, background): “Given the biological significance of aptamer–apatope interactions, it seemed unlikely that Nature had neglected this field of biomolecular recognition and indeed over the past few years we have learned about naturally occurring riboswitche”
TonB-dependent transporters: regulation, structure, and function (2010, background): “Riboswitches are RNA elements that can change conformation upon specific binding of a small molecule (57, 60).”