Cellular and synaptic adaptations mediating opioid dependence.
By John T. Williams, M. Christie, O. Manzoni. Physiological Reviews, 2001
883 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/d4c7cedf628558be420716230e8ef1293871a4ad
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In Cellular and Molecular Neuroscience
In Molecular Biology
Citations in the corpus
- Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance (2013, background): “Nevertheless, longterm use of all MOR agonists produces adverse effects that include the development of tolerance (Williams et al., 2001; von Zastrow et al., 2003; Connor et al., 2004; Waldhoer et al., 2004; Bailey and Connor, 2005; Christie, 2008; Koch and Höllt, 2008; Morgan and Christie, 2011).”
- Reward Processing by the Opioid System in the Brain (2009, neutral): “How does this neuromodulatory system mediate or regulate the rewarding properties of drugs of abuse and contribute to the development of addiction? These questions are being investigated actively; relevant data were reviewed and discussed several years ago (131, 362, 389, 409).”
- Neuropeptide transmission in brain circuits (2012, background): “For instance, mu opioid receptors that respond to met-enkephalin and other related opioid peptides often show fast desensitization of GIRK currents (Williams et al, 2001).”