New from NPG: Genome-wide association study identifies five new schizophrenia loci

By M. Swami. Nature Medicine, 2011

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Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022, result): “Comparison with our earlier studies 11,15 shows increasingly clear contrast between the enrichments in brain and non-brain tissues.”
Power and Predictive Accuracy of Polygenic Risk Scores (2013, result): “It was shown that a large mass, up to half, of all markers in one GWAS could be jointly associated with disease in a second sample, implying a polygenic component to disease risk that justified larger study sizes [4].”