The C2 Domain of PKCδ Is a Phosphotyrosine Binding Domain

By Cyril H. Benes, Ning Wu, A. Elia, T. Dharia, Lewis C. Cantley, S. Soltoff. 2005

222 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d47c354ec09767e1678464c3779bf728dcce856f

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In Molecular Biology

1. S. Steinberg

Citations in the corpus

• Structural Basis of Protein Kinase C Isoform Function (2008, background): “Very recent studies also implicate the PKC C2 domain as a novel phosphotyrosine binding motif that mediates the interaction between PKC and CDCP1 (a transmembrane protein that is tyrosine phosphorylated by Src and overexpressed in colon cancer) (12).”