The Vα14 NKT Cell TCR Exhibits High-Affinity Binding to a Glycolipid/CD1d Complex1

By S. Sidobre, O. Naidenko, B. Sim, N. Gascoigne, K. Garcia, M. Kronenberg. Journal of Immunology, 2002

124 citations recorded by the source corpus.

Subfields: Hematology, Immunology

View Paper: https://www.semanticscholar.org/paper/d44bf668e5543fd76411e5e0b196aec2996533f8

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In Immunology

1. A. Bendelac
2. L. Teyton
3. P. Savage
4. M. Kronenberg

Citations in the corpus

• The biology of NKT cells. (2007, background): “The affinity of interaction between CD1d-αGalCer and mouse TCRs is one of the highest ever recorded for natural TCR/ligand pairs with a Kd ∼100 nM, owing to a slow off rate, for several Vα14-Jα18/Vβ8 combinations examined (50, 51) and may be significantly lower in the human system (∼7 μM) (52).”