Glucose transporters in the 21st Century.
By B. Thorens, M. Mueckler. American Journal of Physiology. Endocrinology and Metabolism, 2010
982 citations recorded by the source corpus.
Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Nephrology
View Paper: https://www.semanticscholar.org/paper/d3dd320b38165cef833bd70ccc240ebcc7ce22d7
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In Endocrinology, Diabetes and Metabolism
In Molecular Biology
In Nephrology
Citations in the corpus
- Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, positive): “Glucose is taken up in the hepatocyte via transporters from the SLC2A family, comprising of 14 members that mostly mediate bidirectional facilitated diffusion of their substrates and GLUT13 acting as a proton-myo-inositol transporter (Thorens and Mueckler 2010).”
- The PI3K/AKT pathway in obesity and type 2 diabetes (2018, background): “AKT directly phosphorylates AS160, inducing GLUT4 translocation, which translocated to the plasma membrane from storage vesicles and transports glucose in skeletal muscle following stimulation of insulin and AKT [38, 39].”
- Glycogen and its metabolism: some new developments and old themes. (2012, background): “Translocation of metabolic enzymes during glycogen synthesis In liver, it is generally accepted that glucose entry into cells is driven by the concentration gradient between the blood and the hepatocyte, based on the kinetic properties of the highKm GLUT2 [67].”
- GLUT2, glucose sensing and glucose homeostasis (2015, background): “Studies of the facilitated diffusion glucose transporters have revealed a multitude of novel regulatory systems controlling glucose homeostasis [17, 97].”
- The Glucose Transporter Glut1 is Selectively Essential for CD4 T Cell Activation and Effector Function (2014, neutral): “The 14 Glut family members are differentially regulated and possess distinct substrates and biological properties (Thorens and Mueckler, 2010).”