DNA methylation: past, present and future directions.

By Keith D. Robertson, P. Jones. Carcinogenesis, 2000

622 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d2c451b4891021e7b84439800f07696f7db72111

How researchers see this paper

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In Genetics

1. Manel Esteller
2. S. Baylin
3. J. Herman

In Molecular Biology

1. Manel Esteller
2. S. Baylin
3. J. Herman
4. M. Soengas
5. Scott W. Lowe
6. W. Gerald
7. Peter A. Jones
8. Peter W. Laird

Citations in the corpus

• DNA methylation and gene silencing in cancer (2005, background): “Preclinical studies have shown that after cellular uptake and phosphorylation, azacitidine is incorporated into RNA, where it suppresses RNA synthesis and has cytotoxic effects”
• Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. (2009, background): “Though not fully understood, this trend of global hypomethylation with regionspecific hypermethylation has been observed previously in cancers (29).”
• Inactivation of the apoptosis effector Apaf-1 in malignant melanoma (2001, background): “Gene silencing that arises from methylation is an important epigenetic mechanism of tumour-suppressor inactivatio”
• Methylation multiplicity and its clinical values in cancer (2021, neutral): “8); RNA methylation primarily modulates RNA processing and decay (Ref.”