Flavonoids: biosynthesis, biological functions, and biotechnological applications
By M. L. Falcone Ferreyra, S. Rius, P. Casati. Frontiers in Plant Science, 2012
1,660 citations recorded by the source corpus.
Flavonoids are widely distributed secondary metabolites with different metabolic functions in plants. The elucidation of the biosynthetic pathways, as well as their regulation by MYB, basic helix-loop-helix (bHLH), and WD40-type transcription factors, has allowed metabolic engineering of plants through the manipulation of the different final products with valuable applications. The present review describes the regulation of flavonoid biosynthesis, as well as the biological functions of flavonoids in plants, such as in defense against UV-B radiation and pathogen infection, nodulation, and pollen fertility. In addition, we discuss different strategies and achievements through the genetic engineering of flavonoid biosynthesis with implication in the industry and the combinatorial biosynthesis in microorganisms by the reconstruction of the pathway to obtain high amounts of specific compounds.
Subfields: Biochemistry, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/d2a8d09c70e006feba241700d9f0e6d3305d29af
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In Biochemistry
In Molecular Biology
Citations in the corpus
- The multidrug and toxic compound extrusion (MATE) family in plants (2014, background): “Due to their importance in plant development, many plants biosynthesize and accumulate flavonoids in a species-specific manner (Falcone Ferreyra et al. 2012).”
- Benefits of Condensed Tannins in Forage Legumes Fed to Ruminants: Importance of Structure, Concentration, and Diet Composition (2019, background): “, 2014) and that expression depends on the plant species and plant parts (Larkin et al., 1997; Gebrehiwot et al., 2002; Abeynayake et al., 2012; Ferreyra et al., 2012; Hancock et al., 2012; Verdier et al., 2012; Cheynier et al., 2013; Harding et al., 2013; Mouradov and Spangenberg, 2014; Pérez-Díaz ”
- Biosynthesis and Regulation of Phenylpropanoids in Plants (2017, background): “…alterations, including root growth, root hair development, root hair length, lateral hair density, shoot organ number, seed organ density, flower organ number, stature and fertility of plants (Murphy et al., 2000; Brown et al., 2001; Buer and Djordjevic, 2009; Falcone Ferreyra et al., 2012).”