PHAT: a transmembrane-specific substitution matrix. Predicted hydrophobic and transmembrane.

By Pauline Crystal Ng, Jorja G. Henikoff, Steven Henikoff. 2000

57 citations recorded by the source corpus.

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1. Mauno Vihinen
2. J. Thusberg
3. Daniel M. Jordan
4. Ayodeji Olatubosun
5. Ivan A. Adzhubei
6. Emidio Capriotti
7. Haiming Tang
8. Abhishek Niroula

Citations in the corpus

• Predicting Functional Effect of Human Missense Mutations Using PolyPhen-2 (2013, methodology): “PolyPhen-2 7.20.28 Supplement 76 Current Protocols in Human Genetics PHAT score PHAT trans-membrane specific matrix (Ng et al., 2000) Measures effect of substitutions in trans-membrane regions; only used for positions annotated as trans-membrane.”
• Performance of mutation pathogenicity prediction methods on missense variants (2011, background): “…includes SWALL database [Johnson and Todd, 2000] annotations for sequence features, a transmembrane predictor TMHMM [Krogh et al., 2001] and PHAT [Ng et al., 2000] transmembrane-specific matrix score for substitutions at predicted transmembrane regions, the Coils2 program [Lupas et al., 1991]…”