B cell receptor signal strength determines B cell fate

By S. Casola, K. Otipoby, M. Alimzhanov, Sibille Humme, N. Uyttersprot, J. Kutok, M. Carroll, K. Rajewsky. Nature Immunology, 2004

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Subfields: Immunology

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Mechanisms of B-cell lymphoma pathogenesis (2005, background): “MALT lymphoma API2–MALT1 (30)135, CD95 (5-80)25,140,141‡ Indirect role of – BCL10–IgH (5)136,137, Helicobactor pylori in MALT1–IgH (15-20)138, gastric MALT FOXP1–IgH (10)139 lymphomas85”
The regulation of IgA class switching (2008, background): “Peyer's patches can also induce IgA class switching through an alternative T-cell-dependent pathway that does not require BCR signals from canonical cognate T-cell–B-cell interactions, but that rather relies on TLR signals from commensal bacteri”