LF power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes

By David S. Goldstein, O. Bentho, M. Park, Y. Sharabi. Experimental Physiology, 2011

817 citations recorded by the source corpus.

Power spectral analysis of heart rate variability has often been used to assess cardiac autonomic function; however, the relationship of low‐frequency (LF) power of heart rate variability to cardiac sympathetic tone has been unclear. With or without adjustment for high‐frequency (HF) power, total power or respiration, LF power seems to provide an index not of cardiac sympathetic tone but of baroreflex function. Manipulations and drugs that change LF power or LF:HF may do so not by affecting cardiac autonomic outflows directly but by affecting modulation of those outflows by baroreflexes.

Subfields: Biomedical Engineering, Cardiology and Cardiovascular Medicine, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/d1ed95a1c9b5682fbc1344e1f3b3efed08290020

How researchers see this paper

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In Biomedical Engineering

1. J. Ginsberg
2. Z. J. Lau
3. Tam Pham
4. Shen-Hsing Annabel Chen
5. Dominique Makowski
6. F. Shaffer

In Cardiology and Cardiovascular Medicine

1. J. Ginsberg
2. Z. J. Lau
3. Tam Pham
4. Shen-Hsing Annabel Chen
5. Dominique Makowski
6. F. Shaffer

In Cognitive Neuroscience

1. J. Ginsberg
2. Z. J. Lau
3. Tam Pham
4. Shen-Hsing Annabel Chen
5. F. Shaffer
6. Dominique Makowski

Citations in the corpus

• The utility of low frequency heart rate variability as an index of sympathetic cardiac tone: a review with emphasis on a reanalysis of previous studies. (2013, background): “Critical reviews of the orthostatic tilt literature (Eckberg, 1997; Goldstein et al., 2011) led to the conclusion that this maneuver is not associated clearly with increased LF power, at least when expressed in absolute units (cf.”
• Heart Rate Variability in Psychology: A Review of HRV Indices and an Analysis Tutorial (2021, result): “In contrast to the assumption that LF power dominantly represents the sympathetic component, research has shown that it is modulated by both ANS branches as well as baroreceptor activities [18,44,53,54].”
• An Overview of Heart Rate Variability Metrics and Norms (2017, background): “LF power may be produced by both the PNS and SNS, and BP regulation via baroreceptors (11, 57, 64, 65), primarily by the PNS (66), or by baroreflex activity alone (67).”