Property distribution of drug-related chemical databases*

By Tudor I. Oprea. J. Comput. Aided Mol. Des., 2000

564 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Organic Chemistry, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/d0c500408210b15b8c604da7c3481d68e574a009

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. M. Namchuk
2. Jürgen Bajorath
3. W. Patrick Walters
4. A. Hopkins
5. Sorel Muresan
6. Shitong Luo
7. Gisbert Schneider
8. Antonio Lavecchia

In Organic Chemistry

1. M. Namchuk
2. Jürgen Bajorath
3. W. Patrick Walters
4. A. Hopkins

In Spectroscopy

1. M. Namchuk
2. Jürgen Bajorath
3. W. Patrick Walters
4. A. Hopkins

Citations in the corpus

• A guide to drug discovery: Designing screens: how to make your hits a hit (2003, background): “Perhaps the best-known example of the filtering approach is the 'rule-of-5' (Ref”
• Quantifying the chemical beauty of drugs. (2012, background): “Analysis of the observed distribution of some key physicochemical properties of approved drugs, including molecular mass ( M r ), hydrophobicity and polarity, reveals that they occupy preferentially a relatively narrow range of possible value”