Synthetic protein scaffolds provide modular control over metabolic flux

By John E. Dueber, Gabriel C. Wu, G. R. Malmirchegini, Tae Seok Moon, Christopher J Petzold, Adeeti V. Ullal, K. Prather, Jay. D. Keasling. Nature Biotechnology, 2009

1,221 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d0a6a2e00710acaf228d76aefc2ff175f9cb2336

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. James J. Collins
2. Ahmad S. Khalil
3. Adam P. Arkin
4. Jay D. Keasling
5. Gabriel C. Wu
6. John E. Dueber
7. Yaakov Benenson
8. James C. Liao

Citations in the corpus

• BglBricks: A flexible standard for biological part assembly (2010, methodology): “As prey, we used HMG CoA reductase (HMGR), N-terminally tagged with an SH3 interaction domain [6].”
• Synthetic biology: applications come of age (2010, background): “In a hybrid rational–combinatorial approach, Dueber et al.(125) suggested that metabolic flux could be controlled by spatially recruiting the enzymes of a desired biosynthetic pathway using synthetic protein scaffolds.”